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Area Four. North of UF Health Proton Therapy Institute

Near Jacksonville International Airport
10-15 minute commute to the Institute

From UF Health Proton Therapy Institute, take either I-95 or Main Street. This area is also near the cruise ship port, Jacksonville Zoo and Budweiser brewery, each of which would enjoy your visit. A brand new mall just opened off Airport Drive, on the other side of I-95. There are many hotels by the airport. The following have worked closely with us to provide the best possible experience and rates for our patients. They are:


A brand new hotel featuring modern design and décor, its hip, trend-setting vibe can be found throughout the rooms, halls, and lobby. Complimentary shuttle within a 9 mile radius as well. Part of the Starwood family of hotels. Ask about the UF Health Medical Discount.

751 Skymark Dr.
Jacksonville, FL 32218


Hampton Inn Suites

13551 Airport Ct.
Jacksonville, FL 32218


Hilton Garden Inn

13503 Ranch Rd.
Jacksonville, FL 32218


Fairfield Inn & Suites by Marriott, Jacksonville Airport

Book online or call the hotel directly to get a great nightly rate. Complimentary airport shuttle and hot breakfast.

1300 Airport Rd.
Jacksonville, FL 32218


Residence Inn by Marriott

Hotel features full kitchens with a stove, microwave, refrigerator and dishwasher in every room. High-speed Internet, outdoor pool and Jacuzzi. Use the on-site fitness center or a local gym at a discounted rate. Pets allowed. Ask about the Proton Therapy Medical discount.

1310 Airport Rd.
Jacksonville, FL 32218


Area One. Near UF Health Proton Therapy Institute

Downtown & historic neighborhoods close to downtown
5 - 15 minute commute to the Institute

Many hotels have worked with us to create the best possible experience for our patients and visitors. Most are within three miles of the Institute, are near the St. Johns River, fine restaurants and entertainment. Downtown Jacksonville, with its Florida Theatre, Performing Arts Center, Ritz Theater, The Jacksonville Landing, Riverwalk, Museum of Contemporary Art, Main Library and sports facilities, has a lot to enjoy, all the time.

Third and Main Apartments (1 mile away) *Discounted Housing Provider*

Located 1 mile from UF Health Proton Therapy Institute, Third & Main is a short-term housing community that specializes in proton patient housing. All of our suites are fully furnished with flat screen TV’s, cable, and secured, reliable Wi-Fi. All utilities are included and each apartment has full-sized appliances and a fully stocked kitchen with cookware & dishes. Washers & dryers in each unit, a gym, library with children’s play area & new dedicated meeting space (event center) for residents to enjoy. As well, there is a fully re-designed, on-site restaurant & bar serving breakfast, lunch and dinner. The complex is fully gated including parking, covered gazebo with fire pit & outdoor grilling area, as well as dog walk. On-site Managers organize social events throughout the week and are here to assist you 24hrs/day for emergencies.

$1530 – $1930/mo, 1br/1 bath – 2br /1 bath, 700 - 1000 sq ft, W/D, Ask about the One Night Rates ($97). See Testimonials! Very flexible with treatment schedules.

1303 N. Main Street
Jacksonville, FL 32206


Hilton Homewood Suites & Hilton Garden Inn

Two Hilton hotels in one location, just a mile from the popular neighborhood of San Marco and a 5 minute drive to Downtown. Homewood Suites offers fine long-term living for its guests, including a full kitchen, complimentary grocery shopping service, wireless and wired Internet, daily maid service, DVD library, fountain pool and spa, exercise facility, business rooms, hot breakfasts, and even dinner on select evenings. Garden Inn, the other half of the Hilton property, provides first class living arrangements for those needing a shorter stay. Ask about the Proton Therapy Medical Discount.

1201 Kings Ave.
Jacksonville, FL


Hyatt Regency Jacksonville, Riverfront

Northbank, on the water. Nearly a thousand rooms and suites, all with the Hyatt Grand Bed and great service. Outdoor pool, whirlpool, sauna, health club, Riverwalk, business center, gift shop, as well as Current Lounge and Plaza III Steakhouse. Fully equipped rooms. Parking extra. You must ask for the "Florida Proton" corporate discount. You cannot get this discount through online booking. It is a significant discount.

225 East Coastline Drive
Jacksonville, FL 32202



Located just steps from the St. Johns River and across the street from Times-Union Performing Arts Center (symphony hall and two theaters) and The Jacksonville Landing. The Omni is a lush hotel with high ratings. Pool, whirlpool, sauna, health club, Riverwalk, business center, restaurants and lounges. Parking is extra. 

245 Water St.
Jacksonville, FL 32202


Hampton Inn by Hilton, Jacksonville Downtown

Southbank. Located downtown Jacksonville with easy access to I-95, just 3 miles away from UF Health Proton Therapy Institute. Near the St. Johns River, fine restaurants and entertainment. Newly renovated, this hotel includes: Complimentary hot buffet breakfast, free high-speed wireless internet, business center, all rooms come equipped with mini microwaves and refrigerators, outdoor pool and on-site fitness center. Use the link below to receive a discounted room rate.

1331 Prudential Dr.
Jacksonville, FL 32207


Extended Stay America, Riverwalk

Southbank near the St. Johns offers the lowest price for our patients for a single night or extended stay. Tell them you are a Proton Therapy patient and they will give you a BIG discount.

1413 Prudential Dr.
Jacksonville, FL 32207


DoubleTree by Hilton Hotel *Discounted Housing Provider*

DoubleTree by Hilton Hotel, Jacksonville Riverfront — Southbank on the water. Walk-out balconies with beautiful views of the river, upgraded sleeping amenities, high-speed and wireless Internet, 24-hour fitness center, riverfront pool, lounges and restaurants. This Hilton property gives UF Health Proton Therapy Institute patients a great nightly rate.

Online reservations for special rate:

1201 Riverplace Blvd.
Jacksonville, FL 32207


Area Three. The Beaches

Neptune Beach, Atlantic Beach, Jacksonville Beach, Ponte Vedra Beach
30-45 minute commute to UF Health Proton Therapy Institute

Neptune and Atlantic beaches are very close, about 13 miles to the east. The drive can be quick and easy, 20 minutes or longer depending on lights, traffic and time of day. Jacksonville Beach is just a few miles farther south. Go here to walk the beach or boardwalk. Ponte Vedra Beach is south of Jacksonville Beach.

Casa Marina

On Jacksonville Beach, this beautifully restored grand dame has already celebrated her 90th birthday and has played host to the best of Jacksonville. Just 16 rooms and suites, each furnished differently. Excellent restaurant, plus a rooftop Tapas bar overlooking the surf, to relax after a day of medical tests. 

691 First St. North
Jacksonville, FL 32250

Ponte Vedra Inn & Club
$$$ - $$$$

A Northeast Florida landmark since its celebrated opening in 1928, this AAA Five-Diamond rated oceanfront resort features 250 luxurious rooms and suites, the Atlantic surf, a beautiful beach, pools, two 18-hole golf courses, tennis, a fitness center, luxury spa, shopping, children's programs, fine dining and award-winning hospitality.

200 Ponte Vedra Blvd.
Ponte Vedra Beach, FL 32082


The Lodge & Club
$$$ - $$$$

Framed by graceful palms and rolling dunes, the oceanfront Lodge & Club features 66 elegantly appointed rooms and suites, many with fireplace and Jacuzzi bath. Resort features include the surf, beach, pools, gym, fine dining and shopping to create a wonderful escape. Access to golf, tennis and spa nearby.

607 Ponte Vedra Blvd.
Ponte Vedra Beach, FL 32082


Best Western

On Jacksonville Beach. Oceanfront rooms just blocks away from The Jacksonville Pier, restaurants, shopping and the SeaWalk Pavilion (outdoor theater and park). This hotel includes complimentary breakfast bar and newspaper, heated outdoor pool, wireless Internet, and free parking. 

305 First St. North
Jacksonville, FL 32250


Palms Retro Hotel

The Palms embraces the past, as each room has its own unique retro theme – from The Rat Pack to Planes, Trains and Automobiles. The quiet courtyard garden and cozy breakfast rooms are a treat.

28 Sherry Drive
Atlantic Beach, FL 32233


Courtyard by Marriott Oceanfront

Located in one of the most popular areas of Jacksonville Beach, the Courtyard by Marriott Oceanfront is situated steps from the amazing Atlantic Ocean. All guest rooms have balconies, complimentary wireless internet, mini frig, microwave and complimentary parking, plus other amenities you expect when staying at a Marriott hotel. Our concierge will be pleased to assist in arranging dinner reservations, transportation or other assistance you may require.  Stop by our Bistro serving Starbucks coffee, breakfast and dinner. Many of our local eateries are within walking distance – a short drive or cab ride of the hotel. If time allows enjoy our heated pool and hot tub overlooking the Ocean.                       

Marriott Reservations – 1-888-236-2427

1617 1st Street North
Jacksonville, FL 32250


Fairfield Inn & Suites by Marriott

The Fairfield Inn & Suites is located directly across the street from the Courtyard by Marriott Oceanfront – just 100 yards from the amazing Atlantic Ocean in one of the most popular areas of Jacksonville Beach. Our guests will enjoy a complimentary Hot Breakfast Buffet served daily, complimentary wireless internet, complimentary parking as well as other amenities you expect when staying at a Marriott hotel. Many of our local eateries are within walking distance - a short drive or cab ride of the hotel. If time allows enjoy our heated pool and hot tub.                                                                                                                                                                                       

Marriott Reservations – 1-888-236-2427

1616 1st Street North
Jacksonville, FL 32250


Area Two. South of the St. Johns River

15-35 minute commute to UF Health Proton Therapy Institute

Most patients, especially those with pre-treatment testing done at the Mayo Clinic, will find accommodations convenient and reasonable. 

Extended Stay America

6961 Lenoir Ave.
Jacksonville, FL 32216


Homewood Suites by Hilton

This property is the only hotel in the St. Johns Town Center™ mall. If you are looking for a place to stay that has everything you need including Internet, cable, breakfast, dinner and a great surrounding atmosphere, then look no further than this Hilton property. Make sure you tell them we sent you to get one of the most competitive rates you can find from a Hilton property.

10434 Midtown Pky.
Jacksonville, FL 32246


Radisson Jacksonville

Located in the heart of Southside Jacksonville on Butler Boulevard. Every room features Sleep Number beds and flat screen HD TV’s, complimentary parking, 24/7 business and fitness center, large pool and outdoor courtyard with heated jacuzzi.

4700 Salisbury Road
Jacksonville, FL 32256